Children’s Hospital of LA
The primary mission of the Stem Cell Core at Children's Hospital Los Angeles (CHLA) is to advance human pluripotent stem cell (hPSC) research by providing comprehensive, tailored support to the CHLA research community. The Core specializes in the custom generation and characterization of induced pluripotent stem cell (iPSC) lines, offering end-to-end services from donor cell reprogramming to quality-controlled iPSC production. In addition, the Core offers expert assistance with directed differentiation protocols, helping researchers generate specific cell types for disease modeling, drug screening, and regenerative medicine applications. The Core also maintains and distributes hESCs and investigator-derived hPSC lines, trains researchers in hPSC culture techniques, conducts rigorous quality control testing, and provides access to well-equipped, professionally maintained tissue culture facilities.
Director: Stefano Da Sacco, sdasacco@chla.usc.edu
